Volume 23 No.1, April 2016


REVIEW ARTICLE

Anaesthesia in early childhood – is the development of the immature brain in danger?

Constantin Bodolea
Department of Anaesthesia and Intensive Care, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

DOI: http://dx.doi.org/10.21454/rjaic.7518.231.chd

Download full article

Abstract

Experimental studies performed on immature animal brains had demonstrated a neurotoxic effect following sedation and general anaesthetics administration. The same magnitude of neurotoxicity has been suggested but not been proven to neonates, infants and small children who have undergone anaesthesia. There is a justified and increasing inquiry regarding the administration of general anaesthesia to paediatric patients.

Keywords: neurotoxicity, general anaesthetics, developing brain, childhood