10. The use of sugammadex in a patient with myasthenia gravis to reverse rocuronium-induced neuromuscular blockade

C. Mitre, Alina Roucaciu, I. Acalovschi

Department of Anaesthesia and Intensive Care I, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca

Abstract

Myasthenia gravis is an autoimmune disease of the neuromuscular junction with unpredictable response to neuromuscular blocking drugs and an increased risk for postoperative residual neuromuscular blockade. We present a patient with ocular myasthenia scheduled for laparoscopic cholecystectomy and rocuronium-induced neuromuscular block in whom administration of 2.0 mg/kg sugammadex intravenously reversed the neuromuscular blockade to a TOF ratio of 0.91 within 60 sec.

Keywords: myasthenia gravis, rocuronium, sugammadex

J Rom Anest Terap Int 2011; 18: 145-148

Utilizarea sugamadexului pentru antagonizarea blocului neuromuscular indus de rocuronium la un pacient cu miastenia gravis