Droperidol versus dexametazone for prevention of PONV
Daniela Ionescu1, Carmen Vasiliniuc3, S. Ciobotea2, I. Acalovschi1
1) Catedra de Anestezie Terapie Intensiva. 2) Medic rezident ATI. 3) Student anul VI, Universitatea de Medicina si Farmacie „Iuliu Hatieganu” Cluj-Napoca
Abstract
Introduction. The purpose of this randomized, double blinded study was to compare the incidence and severity of postoperative nausea and vomiting (PONV) after dexametazone versus droperidol following laparoscopic cholecystectomy.
Methods. 40 patients who underwent a general anaesthesia received prior to induction either 4 mg Dexametazone (group 1) or 1.25 mg Droperidol (group 2). Postoperatively, nausea, vomiting, the degree of pain and the analgesic requirements were assessed for 24 hours.
Results. PONV occurred in 14 patients (70%) in group 2 and in 3 patients (15%) in group 1 (p = 0.024). There was no significant difference between the two groups in the amount of fluids. Preliminary results showed lower needs for analgesia in the dexamethazone group.
Conclusion. We conclude that, compared with droperidol, dexamethaxzone may have a better effect for prevention of PONV in patients undergoing laparoscopic cholecystectomy.
Key words: nausea, vomiting, postoperative analgesia, droperidol, dexametazone
Jurnalul Român de Anestezie Terapie intensivă 2002 Vol.9 Nr.1, 35-39
Profilaxia greţurilor şi vărsăturilor postoperatorii. Droperidol versus Dexametazonă
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